Abstract
A PREVIOUS investigation has shown that phytohæmagglutinin can transform normal human lymphocytes into lymphoblastoid cells1. The normal lymphocyte is highly sensitive to nitrogen mustard (HN2) and to irradiation with small doses of X-rays2. We were, therefore, surprised to find in this work that the derived lymphoblastoid cells are resistant to these reagents.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Schrek, R., and Rabinowitz, Y., Proc. Soc. Exp. Biol. Med. (in the press).
Schrek, R., Friedman, I. A., and Leithold, S. L., J. Nat. Cancer Inst., 20, 1037 (1958).
Schrek, R., Arch. Path., 66, 569 (1958).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SCHREK, R., STEFANI, S. Resistance of Phytohæmagglutinin-treated Lymphocytes to X-rays and Nitrogen Mustard. Nature 200, 482–483 (1963). https://doi.org/10.1038/200482a0
Issue Date:
DOI: https://doi.org/10.1038/200482a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
