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References
Swintosky, J. V., Robinson, M. J., and Foltz, E. L., J. Amer. Pharm. Assoc., 46, 403 (1957).
Chulski, T., Johnson, R. H., Schlagel, C. A., and Wagner, J. G., Nature, 198, 450 (1963).
Butler, T. C., Fed. Proc., 17, 1158 (1958).
Cummings, A. J., and Martin, B. K., Nature, 195, 1104 (1962).
Schachter, D., J. Clin. Invest., 36, 297 (1957).
Schachter, D., and Manis, J. G., J. Clin. Invest., 37, 800 (1958).
Cummings, A. J., in Salicylates an International Symposium, edit. By Dixon, A. St. J., Martin, B. K., Smith, M. J. H., and Wood, P. H. N. (London: Churchill, 1963).
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CUMMINGS, A., MARTIN, B. Excretion and the Accrual of Drug Metabolites. Nature 200, 1296–1297 (1963). https://doi.org/10.1038/2001296a0
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DOI: https://doi.org/10.1038/2001296a0
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