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Establishment and Stability of Chimerism between Two Closely Related Lines of Mice

Abstract

THE Medical Research Council Radiobiology Unit at Harwell recently developed a strain of CBA mice containing the T6 marker chromosomes3,4. They kindly sent a breeding unit to the Chester Beatty Research Institute. This communication concerns a short series of experiments involving descendants of these (CBA/T6T6) mice and the Chester Beatty CBA. The purpose of the experiments was, first, to define the immunological relationship between the strains ; secondly, to describe the conditions under which chimerism could be established between them; thirdly, to investigate the extent and stability of this chimeric state.

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DAVIES, A., DOAK, S. & LEUCHARS, E. Establishment and Stability of Chimerism between Two Closely Related Lines of Mice. Nature 200, 1222–1223 (1963). https://doi.org/10.1038/2001222a0

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  • DOI: https://doi.org/10.1038/2001222a0

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