Abstract
IN order to test for functional competence in thin pieces of isolated tissue containing muscular elements, such as the skin of the rat (which contains smooth muscle and a sheet of skeletal muscle known as the panniculus carnosus)', a bath was devised in which the muscles could be excited directly or indirectly by transmural stimulation1. The response of the stimulated muscle provided a measure of functional competence in the surviving tissue. This bath and also our method of recording the pressure changes developed in it are described here.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Hellmann, K., J. Physiol. (Lond.) (in the press).
Hellmann, K., Brit. J. Pharmacol. (in the press).
Paton, W. D. M., J. Physiol. (Lond.), 127, 40, P (1955).
Hellmann, K., J. Physiol. (Lond.), 165, 11, P (1963).
Hellmann, K., J. Physiol. (Lond.) (in the press).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HELLMANN, K., STEDMAN, J. & DUKE, D. Assessment of Functional Competence in Isolated Muscular Tissues. Nature 199, 494–495 (1963). https://doi.org/10.1038/199494a0
Issue Date:
DOI: https://doi.org/10.1038/199494a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
