Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Synthesis of Complex Organic Compounds from Simple Precursors: Formation of Amino-Acids, Amino-Acid Polymers, Fatty Acids and Purines from Ammonium Cyanide

Nature volume 199, pages 219–222 (1963)Cite this article

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Oparin, A. I., The Origin of Life on Earth (Macmillan, New York, 1938); third ed. (Academic Press, New York, 1957).

    Google Scholar 

  2. Miller, S. L., and Urey, H. C., Science, 130, 245 (1959).

    Article  ADS  CAS  Google Scholar 

  3. Miller, S. L., J. Amer. Chem. Soc., 77, 2351 (1955).

    Article  CAS  Google Scholar 

  4. Abelson, P. H., Science, 124, 935 (1956); Carnegie Inst. Wash. Year Book, No. 55, 111 (1956).

    Google Scholar 

  5. Pavlovskaya, T. E., and Passynsky, A. G., Rep. Moscow Symp. Origin of Life, 98 (Aug. 1957).

  6. Heyns, K., Waltor, W., and Meyer, E., Naturwiss., 44, 385 (1957).

    Article  ADS  CAS  Google Scholar 

  7. Miller, S. L., Biochim. Biophys. Acta, 23, 480 (1957).

    Article  CAS  Google Scholar 

  8. Oro, J., Kimball, A., Fritz, R., and Master, F., Arch. Biochem. Biophys., 85, 115 (1959).

    Article  CAS  Google Scholar 

  9. Oro, J., and Kamat, J. S., Nature, 190, 442 (1961).

    Article  ADS  CAS  Google Scholar 

  10. Garrison, W. M., Morrison, D. C., Hamilton, J. G., Benson, A. A., and Calvin, M., Science, 114, 416 (1951).

    Article  ADS  CAS  Google Scholar 

  11. Kliss, R., and Matthews, C., Proc. U.S. Nat. Acad. Sci., 48, 1300 (1962).

    Article  ADS  CAS  Google Scholar 

  12. Oro, J., Biochem. Biophys. Res. Comm., 2, 407 (1960).

    Article  Google Scholar 

  13. Oro, J., and Kimball, A. P., Arch. Biochem. Biophys., 94, 217 (1961).

    Article  CAS  Google Scholar 

  14. Fox, S. W., and Harada, K., J. Amer. Chem. Soc., 82, 3745 (1960).

    Article  CAS  Google Scholar 

  15. Oro, J., and Guidry, C. L., Nature, 186, 156 (1960).

    Article  ADS  CAS  Google Scholar 

  16. Oro, J., and Guidry, C. L., Arch. Biochem. Biophys., 93, 166 (1961).

    Article  CAS  Google Scholar 

  17. Spackman, O., Stein, W., and Moore, S., Anal. Chem., 30, 1190 (1958).

    Article  CAS  Google Scholar 

  18. Hirs, C. H. W., Moore, S., and Stein, W., J. Amer. Chem. Soc., 76, 6063 (1954).

    Article  CAS  Google Scholar 

  19. Chibnall, A. C., and Rees, M. W., Biochem. J., 68, 105 (1958).

    Article  CAS  Google Scholar 

  20. Bhattacharya, K. R., Datta, J., and Roy, D. K., Arch. Biochem. Biophys., 84, 377 (1959).

    Article  CAS  Google Scholar 

  21. Rydon, H. N., and Smith, P. W. G., Nature, 169, 922 (1952).

    Article  ADS  CAS  Google Scholar 

  22. Reindel, F., and Hoppe, W., Naturwiss., 40, 221 (1953).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Author notes

  1. C. U. LOWE

    Present address: Department of Pediatrics, University of Buffalo., 219 Bryant Street, Buffalo, 22, N.Y.

Authors and Affiliations

  1. Agricultural Research Council Virus Research Unit, Cambridge, England

    C. U. LOWE, M. W. REES &  R. MARKHAM

Authors
  1. C. U. LOWE
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. W. REES
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. MARKHAM
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

LOWE, C., REES, M. & MARKHAM, R. Synthesis of Complex Organic Compounds from Simple Precursors: Formation of Amino-Acids, Amino-Acid Polymers, Fatty Acids and Purines from Ammonium Cyanide. Nature 199, 219–222 (1963). https://doi.org/10.1038/199219a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/199219a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing