Abstract
THE glycolipids of organs outside the central nervous system have been subject to sporadic investigations only. For many years it has been well known that in Gaucher's disease there is a strong accumulation of cerebrosides in spleen. These are glucocerebrosides and not galacto-cerebrosides, the normal constituents of normal brain1. More complex glycosphingosides—ceramide-dihexosides and aminoglycolipids—have been isolated from spleen and red blood cells2–7. With modern chromatographic methods an investigation of the whole glycolipid profile of red blood cell stroma and spleen in different mammals is carried out by Yamakawa and collaborators8,9. Independently of the Japanese group we are investigating the glycosphingolipid profile of human blood serum liver and spleen.
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SVENNERHOLM, E., SVENNERHOLM, L. Neutral Glycolipids of Human Blood Serum, Spleen and Liver. Nature 198, 688–689 (1963). https://doi.org/10.1038/198688b0
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DOI: https://doi.org/10.1038/198688b0
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