Abstract
Two drugs widely used in the chemotherapy of fascioliasis, carbon tetrachloride and hexachloroethane, show very little activity against the immature, migrating forms of the fluke. The earliest age of the fluke against which these drugs are active occurs after migration of the parasite through the liver parenchyma, when the flukes are either in, or about to enter, the bile ducts.
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References
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WILLIAMS, V. Effect of 4,4′-Diaminodiphenylmethane against Fasciola hepatica in the Rabbit and in Cattle. Nature 198, 203–204 (1963). https://doi.org/10.1038/198203b0
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DOI: https://doi.org/10.1038/198203b0
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