Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Gel-filtration of the α-Toxin of Clostridium oedematiens Type B

Abstract

Clostridium oedematiens is among the most fastidious of the pathogenic anaerobes, and it is probably mainly for this reason that no chemical investigations on its lethal (α-)toxin appear to have been carried out. Other reasons for this neglect are to be found among the observations made by Walbum and Reymann1, who remarked that the toxin is stable only within a narrow range of pH values and is quickly destroyed even at moderately elevated temperatures.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Walbum, L. E., and Reymann, G. C., J. Path., 44, 379 (1937).

    Article  CAS  Google Scholar 

  2. Kohn, J., Nature, 183, 1055 (1959).

    Article  ADS  CAS  Google Scholar 

  3. Green, A. A., J. Amer. Chem. Soc., 55, 2331 (1933).

    Article  CAS  Google Scholar 

  4. Putnam, F. W., Lamanna, C., and Sharp, D. G., J. Biol. Chem., 165, 735 (1946).

    CAS  PubMed  Google Scholar 

  5. Shemanova, G. F., and Blagoveshchenskii, V. A., Biokhimiya, 22, 799 (1957).

    CAS  Google Scholar 

  6. Fischer, E. H., and Stein, E. A., in The Enzymes, edit. by Boyer, P. D., Lardy, H., and Myrbäck, K., 4, 301 (Academic Press, Inc., New York, 1960).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

PHILLIPS, A., BATTY, I. Gel-filtration of the α-Toxin of Clostridium oedematiens Type B. Nature 198, 1200–1201 (1963). https://doi.org/10.1038/1981200a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1981200a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing