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Increased Survival-time in Dystrophic Mice treated with Methylandrostenediol Dienanthoylacetate

Abstract

ANABOLIC steroids have been noted to increase survival time in dystrophic mice, Jax/129 (dydy), but the disease syndrome was not otherwise altered. Testosterone propionate did not possess this ability1,2. It was of interest to evaluate an anabolic steroid, 17-α-methylandrostene-5-diol-3β-17β-dienanthoylacetate (MADD), which has a prolonged period of activity.

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BORGMAN, R. Increased Survival-time in Dystrophic Mice treated with Methylandrostenediol Dienanthoylacetate. Nature 197, 1304–1305 (1963). https://doi.org/10.1038/1971304b0

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