Abstract
THE animal virus vesicular stomatitis can be easily propagated in tissue cultures and quantitatively assayed by the plaque-count technique using tissue cell monolayers1,2. In preliminary experiments dealing with X-ray inactivation of vesicular stomatitis virus, several morphological plaque-type variants were observed among the irradiated survivors. This observation suggested that vesicular stomatitis virus offers additional material for radiobiological and genetic studies on animal viruses and dictated a quantitative study of the plaque-forming ability of vesicular stomatitis virus when irradiated under a number of conditions suitable for the quantitative estimation and subsequent isolation of plaque-type variants.
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SHECHMEISTER, I., JOHN, R. & PITTMAN, D. Effect of X-Rays on Plaque-forming Ability of Vesicular Stomatitis Virus. Nature 194, 113–114 (1962). https://doi.org/10.1038/194113a0
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DOI: https://doi.org/10.1038/194113a0
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