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Rapid Procedure for Monitoring Steroid Transformations

Abstract

THE Δ1 dehydrogenation of 12α-fluoro,llβ-hydroxytestosterone by C. simplex is an extremely fast reaction. Peak conversion to product may occur within 1 hr. after addition of the substrate. Furthermore, the product is quickly degraded after the reaction is completed. A reaction of this type requires a rapid method of determining harvest time.

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ROBERTS, H., ROBISON, R. Rapid Procedure for Monitoring Steroid Transformations. Nature 194, 88–89 (1962). https://doi.org/10.1038/194088a0

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