Abstract
ELECTRON microscopic evidence indicates that the formation of melanin granules in melanocytes occurs in a region of the cell associated with the Golgi membranes1,2. Although the characteristic flattened sacs and vesicles of this structure are evident in many types of vertebrate and invertebrate cells, the vesicular profiles are particularly apparent in cells concerned with secretion and absorption3, and differ in several morphological respects from the endoplasmic reticulum4. The biochemical composition and role of this membrane structure in the formation of melanin granules are not yet established.
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KARASEK, M., HULTIN, T. In vivo and in vitro Incorporation of Amino-Acids by Melano-Protein Particles of the Harding–Passy Mouse Melanoma. Nature 194, 87–88 (1962). https://doi.org/10.1038/194087a0
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DOI: https://doi.org/10.1038/194087a0
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