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Acid Mucopolysaccharides of Invertebrate Cartilage

Nature volume 193, pages 378–379 (1962)Cite this article

Abstract

PREVIOUS biochemical studies of acid mucopolysaccharides of cartilage were largely limited to mammalian tissues1. The principal polysaccharides found were chondroitin sulphate A and chondroitin sulphate C, with keratosulphate a minor component. The wide distribution of these acid mucopolysaccharides among all vertebrate classes, as shown by a preliminary survey2, suggests that their presence may be a systematic characteristic of vertebrate cartilage. Thus far only cartilages of elasmobranchs and lampreys have been found to contain sulphated chondroitin sulphate C type polysaccharides; sulphated keratosulphate is present in elasmobranchs only. These polysaccharides are similar to chondroitin sulphate C and keratosulphate, respectively, except for an excess of ester sulphate, above one mole per mole hexosamine.

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Authors and Affiliations

  1. LaRabida-University of Chicago Institute and Department of Biochemistry, University of Chicago,

    M. B. MATHEWS & J. DUH

  2. Veterans Administration Hospital, Special Dental Research Program, Brooklyn, New York

    P. PERSON

Authors
  1. M. B. MATHEWS
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  2. J. DUH
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  3. P. PERSON
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MATHEWS, M., DUH, J. & PERSON, P. Acid Mucopolysaccharides of Invertebrate Cartilage. Nature 193, 378–379 (1962). https://doi.org/10.1038/193378a0

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