Abstract
RECENTLY the ‘D-like’ antibody was demonstrated in the sera of guinea pigs injected with random Rh-positive, Rh-negative human red cells and the red cells of rhesus monkeys1. The ‘D-like’ antibody was produced also in guinea pigs injected with heat (50° C.) extracts of washed Rh-positive or Rh-negative red cells. Murray and Clark2 demonstrated that the antigenicity of heat extracts resided in the sediments obtained at 30,000g. These findings were confirmed and extended by Levine et al.1,3.
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References
Levine, P., Celano, Marino, Fenichel, R., and Singher, R., Science, 133, 332 (1961).
Murray, J., and Clark, E. C., Nature, 169, 887 (1952).
Levine, P., Celano, M., Fenichel, R., Pollack, W., and Singher, H., J. Immunol., 87, 747 (1961).
Wiener, A. S., and Gordon, E. B., Amer. J. Clin. Path., 23, 429 (1953).
Levine, P., and Celano, M. (unpublished results).
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Argall, C. I., Ball, J. M., and Trentelman, E., J. Lab. Clin. Med., 41, 895 (1953).
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Vos, G. H., Vos, E. I. W., Kirk, R. L., and Sanger, R., Lancet, i, 14 (1961).
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LEVINE, P., CELANO, M. Presence of ‘D-like’ Antigens on Various Monkey Red Blood Cells. Nature 193, 184–185 (1962). https://doi.org/10.1038/193184a0
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DOI: https://doi.org/10.1038/193184a0
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