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Hydrolysis of Glycerides of C-16 and C-18 Fatty Acids by Post-Heparin Plasma

Abstract

SEVERAL investigators have demonstrated that intravenous injection of heparin releases into the plasma of man and several other species a lipase (clearing factor lipase, lipoprotein lipase) which hydrolyses the glyceride moieties of some lipoproteins1. It has also been reported that various triglyceride emulsions, for example, coconut and olive oils, are substrates for the enzyme and that activation of the emulsion with serum high-density lipoproteins increases the rate of hydrolysis of the triglycerides.

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References

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SHORE, B., SHORE, V. Hydrolysis of Glycerides of C-16 and C-18 Fatty Acids by Post-Heparin Plasma. Nature 193, 163–164 (1962). https://doi.org/10.1038/193163a0

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