Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effect of Enzyme Injections on Mitosis in Regenerating Liver

Nature volume 191, pages 400–401 (1961)Cite this article

Abstract

THE addition of deoxyribonuclease to tissue-culture media affected mitosis in tissue cultures1,2. In mice bearing Ehrlich ascites tumours, injections of the enzyme decreased the incidence of mitoses in the tumour cells and increased the survival-time of the animals3. Similarly, injections of xanthine oxidase and ribonuclease affected the rate of tumour growth and the survival time4–6.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Chevremont, M., Chevremont-Comhaire, S., and Backeland, E., C.R. Acad. Sci., Paris, 247, 2197 (1958).

    CAS  Google Scholar 

  2. Montgomery, P. O'B., and Bonner, W. A., Proc. Amer. Assoc. Cancer Res., 3, 44 (1959).

    Google Scholar 

  3. de Lamirande, G., Proc. Amer. Assoc. Cancer Res., 3, 105 (1960).

    Google Scholar 

  4. Haddow, A., et al., Brit. Empire Cancer Campaign Ann. Rep., 31, 35 (1953); 32, 50 (1954).

    Google Scholar 

  5. Haddow, A., de Lamirande, G., Bergel, F., Bray, R. C., and Gilbert, D. A., Nature, 182, 1144 (1958).

    Article  ADS  CAS  Google Scholar 

  6. Ledoux, L., Nature, 175, 258 (1955) ; 176, 36 (1955).

    Article  ADS  CAS  Google Scholar 

  7. Higgins, G. M., and Anderson, R. M., Arch. Path., 12, 186 (1931).

    Google Scholar 

  8. Jaffe, J., Anat. Rec., 120, 953 (1954).

    Article  Google Scholar 

  9. de Lamirande, G., Allard, C., and Cantero, A., Cancer Res., 18, 952 (1958).

    CAS  PubMed  Google Scholar 

Download references

Author information

Author notes

  1. GASTON DE LAMIRANDE: Research Associate of the National Cancer Institute of Canada.

Authors and Affiliations

  1. Montreal Cancer Institute, Research Laboratories, Notre Dame Hospital and University of Montreal, Montreal

    GASTON DE LAMIRANDE

Authors
  1. GASTON DE LAMIRANDE
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

DE LAMIRANDE, G. Effect of Enzyme Injections on Mitosis in Regenerating Liver. Nature 191, 400–401 (1961). https://doi.org/10.1038/191400b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/191400b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing