Abstract
RECENT work in this laboratory has shown that, in the mouse, ethanol-1-14C is incorporated in vivo into phospholipids, cholesterol, and fatty acids at approximately the same rate and to the same degree as acetate-1-14C (ref. 1). It is well known that in diabetic animals a metabolic block exists in the synthesis of fatty acids from acetate2. It was of interest to determine whether ethanol can be used to any greater degree as a source of building blocks for fatty acid synthesis in diabetic animals, or whether a similar metabolic block occurs.
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References
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SMITH, M. Incorporation of Ethanol-1-14C into Fatty Acids in the Normal and Alloxan Diabetic Rat. Nature 190, 273–274 (1961). https://doi.org/10.1038/190273a0
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DOI: https://doi.org/10.1038/190273a0
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