Abstract
RENDEL1 attempted to produce hæmolytic disease of the new-born lamb by injecting 8 pregnant ewes with blood taken from the rams to which they were mated. As a result, 4 of the ewes produced immune antibodies which reacted with the red cells of their mates; but their lambs did not develop hæmolytic disease even though at least 2 of them ingested colostrum-containing antibodies which reacted weakly in vitro with their respective red cells. In these cases, no antibody could be detected on the lambs' red cells, and Rendel concluded that if hæmolytic disease occurred in lambs it must be rare.
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References
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TUCKER, E. An Attempt to produce Hæmolytic Disease in Lambs. Nature 189, 847–848 (1961). https://doi.org/10.1038/189847a0
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DOI: https://doi.org/10.1038/189847a0
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