Abstract
FOR many years bee venom has been used in the treatment of arthritis and rheumatism, but with little evidence of its value1. Bee venom contains three important constituents : the main toxic fraction I, and the enzyme fraction II, containing phospholipase and hyaluronidase. Each enzyme has been isolated in pure form2,3. The hæmolytic effect of the venom on blood corpuscles is caused directly by the toxic fraction I, and indirectly by the phospholipase-A activity4. Among other effects of phospholipase-A. is retardation of egg yolk coagulation5.
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References
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El Karemi, M. M. A., dissertation for doctorate, Würzburg (1957).
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MOHAMMED, A., EL KAREMI, M. Immunity of Bee Keepers to Some Constituents of Bee Venom : Phospholipase-A Antibodies. Nature 189, 837–838 (1961). https://doi.org/10.1038/189837b0
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DOI: https://doi.org/10.1038/189837b0
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