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Immunological Cross-Reactions between Salk ‘Altered’ Monkey Heart Cells and Ehrlich Ascites Carcinoma Cells

Abstract

RECENT work1 has shown that the metabolism of Ehrlich ascites carcinoma cells (EA cells) can be inhibited by small quantities of specific antiserum in the presence of complement. We have now observed that antisera prepared against the Salk ‘altered’ monkey heart cells (MHS cells)2 show activity not only against the homologous cells, but also against Ehrlich ascites carcinoma cells and HeLa cells as well.

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References

  1. Bickis, I. J., Quastel, J. H., and Vas, S. I., Cancer Res., 19, 602 (1959).

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  2. Salk, J. E., and Ward, E. N., Science, 126, 1338 (1957).

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  3. Defendi, V., and Colter, J. S., J. Nat. Cancer Inst., 23, 411 (1959).

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JOHNSTONE, R., VAS, S. Immunological Cross-Reactions between Salk ‘Altered’ Monkey Heart Cells and Ehrlich Ascites Carcinoma Cells. Nature 189, 70–71 (1961). https://doi.org/10.1038/189070a0

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  • DOI: https://doi.org/10.1038/189070a0

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