Abstract
ALTHOUGH vitamin A acid plays no part in the visual cycle1, it is active in the systemic functions of vitamin A in that it maintains normal growth and skin appearance1,2. With Prof. R. A. Morton, we have found (unpublished work) that vitamin A acid also prevents the rise of ubiquinone concentration in rat liver, a characteristic effect of vitamin A deficiency3.
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References
Dowling, J. E., and Wald, G., Proc. Fourtn Int. Cong. Biochem., 11, 185 (1960).
Arens, J. F., and Van Dorp, D. A., Nature, 158, 60, 622 (1946).
Heaton, F. W., Lowe, J. S., and Morton, R. A., Biochem. J., 67, 208 (1957). Morton, R. A., and Phillips, W. E. J., Biochem. J., 73, 416 (1959).
Nieman, C., and Klein Obbink, H. J., Vitam. and Horm., 12, 69 (1954).
Moore, T., in Symposium in Nutrition, edit. by Herriott, R. M., 55 (Johns Hopkins Press, Baltimore, 1953).
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THOMPSON, J., PITT, G. Vitamin A Acid and Hypervitaminosis A. Nature 188, 672–673 (1960). https://doi.org/10.1038/188672b0
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DOI: https://doi.org/10.1038/188672b0
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