Abstract
THE introduction of a cannula into a very small vein (< 1 mm.) is almost impossible because of collapse and cohesion of the vessel walls. Any looping or clamping of the vein beyond the incision in order to avoid bleeding and to maintain a clear visual field causes spasm which will not permit further passage of the tubing into the vascular lumen. If the cannula is forced, it will perforate the thin vessel. We have, therefore, constructed a cannulating device which permits the introduction of a fine plastic tubing into a small vessel without visual control.
Similar content being viewed by others
Article PDF
References
Najar, L., and Rappaport, A. M., Proc. Soc. Exp. Biol. and Med. 95, 65 (1957).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ROSS, P., RAPPAPORT, A. Cannulation of Minute Mesenteric Veins for Continuous Portal Perfusion of Rats. Nature 188, 326 (1960). https://doi.org/10.1038/188326a0
Issue Date:
DOI: https://doi.org/10.1038/188326a0
This article is cited by
-
Die quantitative Bestimmung des Stoffumsatzes in der Leber am nichtanaesthesierten, frei beweglichen Kaninchen
Pfl�gers Archiv f�r die Gesamte Physiologie des Menschen und der Tiere (1967)
-
Liver Metabolism of Anticholinesterase Compounds in Live Rats : Relation to Toxicity
Nature (1966)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.