Abstract
PREVIOUS reports from these laboratories1,2 have indicated the thyroid response to thyrotrophic hormone, as measured by uptake of phosphorus-32 (ref. 3), to be increased in sialoadenectomized animals when compared with intact controls. Hypophysectomy and hypophysectomy plus sialoadenectomy gave identical results as regards iodine trapping by rat thyroid, but the ratio of thyroid organic iodine-131 to inorganic iodine-131 indicated that sialoadenectomy reduced the synthesis of organically bound iodine-131 (ref. 4). To date, our observations have indicated some change in the modus operandi of thyrotrophic hormone in animals whose salivary glands have been removed. To obtain further information regarding the role of thyrotrophic hormone in sialex animals, it was decided to investigate the distribution of labelled hormone therein.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Wase, A. W., and Feng, L., Nature, 178, 1395 (1956).
Wase, A. W., and Feng, L., Nature, 177, 624 (1956).
Barell, U., and Holmgren, H., Acta Endocrin., 3, 331 (1949).
Wase, A. W., and Feng, Y. S. L., Acta Endocrin., 23, 413 (1956).
Hughes, W. L., Ann. N.Y. Acad. Sci., 70, 3 (1957).
Steinfield, J. L., Paton, R. R., Flick, A. L., Milch, R. A., Beach, F. E., and Tabern, D. L., Ann. N.Y., Acad. Sci., 70, 109 (1957).
Baker, B. L., and Abrams, G. D., International Symposium, Hypophyseal Growth Hormones, Nature and Actions, 107 (McGraw-Hill, 1954).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WASE, A., FENG, Y. Sialoadenectomy and the Distribution of Thyrotrophin labelled with Iodium-131. Nature 187, 778–780 (1960). https://doi.org/10.1038/187778b0
Issue Date:
DOI: https://doi.org/10.1038/187778b0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.