Abstract
THE electrodialyser previously described1 has been used for desalting samples of urine prior to chromatography. This apparatus (obtainable from Shandon Scientific Co., Ltd., 6 Cromwell Place, London, S.W.7) was used successfully in the desalting of tissue extracts ; but Smith2, using a modified version of the desalter, reported considerable losses of amino-acids during desalting of urine. It was considered desirable to repeat the experiments in the original apparatus by plotting the ‘desalting curve’ and submitting samples desalted for varying lengths of time to two-dimensional chromatography.
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References
Wood, T., Biochem. J., 62, 611 (1956).
Smith, I. (ed.), “Chromatographic Techniques, Clinical and Biochemical Applications” (Heinemann, London, 1958).
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WOOD, T. Desalting of Urine by Electrodialysis. Nature 186, 634–635 (1960). https://doi.org/10.1038/186634a0
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DOI: https://doi.org/10.1038/186634a0
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