Abstract
THE suckling mouse absorbs antibody readily when whole immune serum is administered by mouth1 and transmission to the circulation is selective in the sense that antibodies prepared in a variety of species are characterized by different concentration quotients in the recipient plasma2. During the course of the work with serum protein preparations labelled with iodine-131 in other species a criterion of the physiological integrity of the labelled material was sought which would be sensitive and readily determined. Recourse was therefore made to gut transmission in the young mouse.
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Morris, I. G., Proc. Roy. Soc., B, 148, 84 (1957).
Hemmings, W. A., and Morris, I. G., Proc. Roy. Soc., B, 150, 403 (1959).
McFarlane, A. S., Biochem. J., 62, 135 (1956).
Kekwick, R. A., Biochem. J., 34, 1248 (1940).
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HEMMINGS, W. Selection of Iodinated Protein in the Young Mouse. Nature 186, 399 (1960). https://doi.org/10.1038/186399a0
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DOI: https://doi.org/10.1038/186399a0
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