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Early Injury of Chromoexcretion after Total Irradiation of Rats

Abstract

IT is claimed by all available literature that damage occurs to the function of the liver after whole-body irradiation by doses, approaching LD100, from as late as the stage of development of the secondary post-radiation changes1,2. Some biochemical results, however, support the opinion that the liver cell should be damaged in its function at the earliest stage of an acute irradiation disturbance3–5. To prove the early functional lesion we carried out experiments with bengal rose tagged with radioactive iodine-131.

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DIENSTBIER, Z., ANDRYSEK, O. Early Injury of Chromoexcretion after Total Irradiation of Rats. Nature 185, 630–631 (1960). https://doi.org/10.1038/185630a0

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