Abstract
STUDIES of infra-red absorption spectra of immunopolysaccharides have received little attention until recently. Thus, Levine, Stevenson and Kabler1 were able to show that the serologically reactive and type specific pneumococcal polysaccharides have distinctive spectra by which they can be identified. Later, Watson, Marinetti and Scherp2 working with the specific hapten of group C meningococcus were successful in assigning a provisional structure for the hapten by the aid of infra-red spectral analysis. Inasmuch as purified cryptococcal polysaccharides have shown serological reactivity by precipitation with specific hyperimmune rabbit serum3,4 in addition to stimulating antibody formation in mice5, it was deemed desirable to investigate their infra-red spectra and to compare these with the spectra of crude preparations.
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References
Levine, S., Stevenson, H. J. R., and Kabler, P. W., Arch. Biochem., 45, 65 (1953).
Watson, R. G., Marinetti, G. V., and Scherp, H. W., J. Immunol., 81, 337 (1958).
Neill, J. M., Castillo, G. G., Smith, R. H., and Kapros, C. E., J. Exp. Med., 89, 93 (1949).
Evans, E. E., and Kessel, J. F., J. Immunol., 67, 109 (1951).
Gadebusch, H. H., J. Infect. Dis., 102, 219 (1958).
Sevag, M. G., Lackman, D. B., and Smolens, J., J. Biol. Chem., 124, 425 (1938).
Evans, E. E., Proc. Soc. Exp. Biol. Med., 71, 644 (1949).
Stevenson, H. J. R., and Levine, S., Science, 116, 705 (1952).
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GADEBUSCH, H. Infra-red Spectra of Capsular Polysaccharides from Thirteen Strains of Cryptococcus neoformans . Nature 185, 610–612 (1960). https://doi.org/10.1038/185610b0
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DOI: https://doi.org/10.1038/185610b0
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