Abstract
DURING regeneration of crushed nerve-fibres of spinal ganglion cells, the turnover rate of proteins in the ganglia (C.7 and C.8) increases extensively, as compared with the controls1. This finding, on one hand, justifies the increase in protein in the perikaryon of the regenerating neuron1,2; on the other hand, it supports Weiss's opinion3 that some of the new proteins leave the body-cell and reach the growing end of the axon.
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Miani, N., Rizzoli, A., and Bucciante, G., J. Neurochem. (in the press).
Brattgård, S.-O., Edström, J.-E., and Hydén, H., J. Neurochem., 1, 316 (1957).
Weiss, P., and Hiscoe, H. B., J. Exp. Zool., 107, 315 (1948).
Gerard, R. W., in Weiss, P., “Genetic Neurolog.” (Univ. of Chicago Press, Chicago, 1950).
Samuels, A. J., Boyarrsky, L. L., Gerard, R. W., Libet, B., and Brust, M., Amer. J. Physiol., 164, 1 (1951).
Krebs, H. A., and Henseleit, K., Hoppe-Seyl. Z. physiol. Chem., 210, 33 (1932).
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MIANI, N. Proximo-Distal Movement along the Axon of Protein synthesized in the Perikaryon of Regenerating Neurons. Nature 185, 541 (1960). https://doi.org/10.1038/185541a0
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DOI: https://doi.org/10.1038/185541a0
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