Abstract
BIOLOGICAL photosensitized reactions are known to result from the absorption of a wide spectrum of radiation. The energy and therefore the wave-length of light absorbed and the biological changes occurring in photosensitized reactions are obviously closely related. A fundamental law of photochemistry, the Grotthus–Draper law, states that only radiation absorbed by the reacting system is effective in producing chemical change. Thus the radiation producing the photosensitizing reaction (that is, the action spectrum) should correspond to the absorption spectrum of the photosensitizing agent.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Fitzpatrick, T. B., Hopkins, C. E., Blickenstaff, D. D., and Swift, S., J. Invest. Dermat., 25, 187 (1955).
Psoralens and Radiant Energy; Proceedings of a Symposium, J. Invest. Dermat., 32, 132 (1959).
Musajo, L., Rodighiero, G., and Caporale, G., Bull. Soc. Chim. Biol., 38, 1213 (1954).
Pathak, M. A., and Fowlks, W. L. (in the press).
Pathak, M. A., and Fellman, J. H. (to be published).
Fowlks, W. L., Griffith, D. G., and Oginsky, E. L., Nature, 181, 571 (1958).
Chakraborty, D. P., Das Gupta, A., and Bose, P. K., Ann. Biochem. and Exp. Med., 17, 57 (1957).
O'Neal, M. A., and Griffin, A. C., Cancer Res., 17, 911 (1957).
Pathak, M. A., Daniels, F., jun., Hopkins, C. E., and Fitzpatrick, T. B., Nature, 183, 728 (1959).
Pathak, M. A., and Fitzpatrick, T. B., J. Invest. Derm., 32, 509 (1959).
Pathak, M. A., Fellman, J. H., and Kaufman, K. D. (in the press).
Bowman, R. L., Caulfield, P. A., and Udenfriend, S., Science, 122, 32 (1955); 122, 972 (1955).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PATHAK, M., FELLMAN, J. Activating and Fluorescent Wave-lengths of Furocoumarins : Psoralens. Nature 185, 382–383 (1960). https://doi.org/10.1038/185382a0
Issue Date:
DOI: https://doi.org/10.1038/185382a0
This article is cited by
-
Biologic Action Spectra of 8-Methoxypsoralen Determined by Monochromatic Light**From the Departments of Dermatology and Pathology, Baylor University College of Medicine, Houston, Texas.
Journal of Investigative Dermatology (1968)
-
Announcements
Journal of Investigative Dermatology (1968)
-
Effect of Structural Alterations on the Photosensitizing Potency of Furocoumarins (psoralens) and Related Compounds
Journal of Investigative Dermatology (1967)
-
Molecular Orbital Calculations on Photosensitizing Psoralen Derivatives
Nature (1966)
-
Absorption and Emission Spectra of Psoralen and 8-Methoxypsoralen in Powders and in Solutions**From the Biophysics Department, Michigan State University, East Lansing, Michigan.
Journal of Investigative Dermatology (1965)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.