Distribution of Gm^a and Gm-like among Javanese, Djuka Negroes, and Oyana and Carib Indians

Abstract

Grubb and Laurell¹ and others have demonstrated that some human sera contain a genetically determined factor capable of inhibiting the ability of serum from selected rheumatoid arthritic patients (RA serum) to agglutinate Rh(+) cells coated with selected incomplete anti-D sera. They called this factor Gm^a and showed that its presence is due to a dominant gene. Thus far various investigators have tested 2,635 Europeans and found that 56.96 per cent were Gm(a+)². Grubb and Laurell¹ found 95 per cent of 74 Eskimos to be Gm(a+), and Steinberg and Giles² found 98 per cent of 98 American Negroes to be Gm(a+).