Abstract
GENETIC recombination between mutant strains of Escherichia coli strain K12 is governed by a system of mating types1,2. The first two mating types to be discovered were called F+ and F−. In crosses the F− F+ parent donates genetic material to the F− parent. The progeny are predominantly F+. At the same time it was discovered that the Ffactor was infectious, that is, if F+ and F− strains were mixed and the organisms of the F− strain re-isolated, a proportion had become F+. It was therefore possible that the F+ state of the progeny was secondary and that any F-zygotes became infected by other F+ cells.
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References
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REEVES, P. Role of Hfr Mutants in F+×F− Crosses in Escherichia coli K12. Nature 185, 265–266 (1960). https://doi.org/10.1038/185265b0
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DOI: https://doi.org/10.1038/185265b0
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