Abstract
THE presence, in various animal tissues not primarily hæmatopoietic, of some or all of the enzyme systems taking part in porphyrin and hæm biosynthesis has been reported by many authors. However, until recently, any investigation of porphyrin biosynthesis in the leucocyte has been hindered by the contamination of tissue preparations with erythrocytes having a much greater synthetic capacity. During a systematic study of several enzyme systems in the normal and pathological leucocyte now being carried out in this clinic, a method of preparing undamaged leucocytes, completely free of erythrocytes and thrombocytes, has been developed1. It therefore seemed interesting to study the behaviour of these enzyme systems in this readily available and easily quantitated tissue.
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References
Borel et al., Acta Med. Internisten, 063/31 (1959).
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CULLITY, B., VANNOTTI, A. Porphyrin Biosynthesis in the Leucocyte. Nature 185, 187–188 (1960). https://doi.org/10.1038/185187a0
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DOI: https://doi.org/10.1038/185187a0
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