Abstract
IT was shown by Baisden1 that the addition of traces of bacillary ash to a synthetic medium prepared from chemically pure constituents was a very effective stimulant for the growth of Mycobacteria, and similar results could be obtained with a mixture of fourteen pure inorganic salts. Various other workers have demonstrated the growth-promoting effect of metal ions, especially zinc2–4 and manganese5. A simpler mixture of pure inorganic salts than that used by Baisden has been described recently by Paterson et al. 6. This is as effective an addition to Dorset's7 medium for growing large quantities of human type bacilli for the production of tuberculin as is Baisden's.
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References
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PATTERSON, D. Influence of Cobalt and Zinc Ions on the Growth and Porphyrin Production of Mycobacterium tuberculosis avium . Nature 185, 57 (1960). https://doi.org/10.1038/185057a0
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DOI: https://doi.org/10.1038/185057a0
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