Abstract
DIETHYLSTILBŒSTROL has been reported previously by Nicol et al. 1,2 to have a strong stimulative action on the phagocytic activity of the reticulo-endothelial system, and various steroids having high œstrogenicity have also been shown to have a similar action3. The present research was planned to determine the minimum dose of diethylstilbcestrol required to stimulate the reticulo-endothelial phagocytes and to ascertain its relationship to the œstrogenic potential of the substance.
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References
Nicol, T., Helmy, I. D., and Abou-Zikry, A., Brit. J. Surg., 40, 166 (1952).
Nicol, T., Bilbey, D. L. J., and Ware, C. C., Nature, 181, 1538 (1958).
Bilbey, D. L. J., and Nicol, T., Nature, 182, 674 (1958).
Biozzi, G., Benacerraf, B., and Halpern, B. N., Brit. J. Exp. Path., 34, 441 (1953).
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NICOL, T., WARE, C. Minimum Dose of Diethylstilbœstrol required to stimulate the Phagocytic Activity of the Reticulo-Endothelial System. Nature 185, 42–43 (1960). https://doi.org/10.1038/185042a0
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DOI: https://doi.org/10.1038/185042a0
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