Abstract
Using methyl and carboxyl labelled acetate, Grob and Butler1,2 have shown that both carbon atoms of acetate are extensively incorporated into β-carotene synthesized by Mucor heimalis. They also found that pantothenic acid and pantetheine stimulate β-carotene synthesis; on the basis of this fact they have suggested that coenzyme A is involved in carotenogenesis. Studies have therefore been made to investigate the role of coenzyme A in the biogenesis of carotenoids; the present study details the results of the experiments on carotene biosynthesis using extracts prepared from carrots (Daucus carota).
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References
Grob, E. C., and Butler, R., Helv. Chim. Acta, 8, 1313 (1955).
Grob, E. C., and Butler, R., Helv. Chim. Acta, 7, 1908 (1955).
Lepage, G. A., Biochem. Prep., 1, 5 (1949).
Friend, J., Goodwin, T. W., and Griffiths, L. A., Biochem. J., 60, 649 (1955).
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MODI, V., PATWA, D. Biosynthesis of Carotenes in Carrot Extracts. Nature 184, 983–984 (1959). https://doi.org/10.1038/184983b0
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DOI: https://doi.org/10.1038/184983b0
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