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Subcutaneous Absorption of Urethane in Dehydrated and Fasted Mice

Nature volume 184, pages 646–647 (1959)Cite this article

Abstract

THE absorption of the non-electrolyte urethane from subcutaneously injected solutions is depressed in mice treated with œstrogenic hormones in pharmacological doses1. This is possibly due to the higher amount of connective tissue ground substance found in such animals when compared with controls. Both the hexosamine content and the concentration of water in the connective tissue is increase following treatment with œstrogen. To elucidate the influence of alterations in the content of hexosamine and the concentration of water on the absorption from subcutaneously injected solutions of a non-electrolyte, the following experiments were carried out.

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References

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Authors and Affiliations

  1. Department of Pharmacology, University of Copenhagen, 20, Juliane Maries Vej

    EIGILL HVIDBERG & JENS SCHOU

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  1. EIGILL HVIDBERG
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  2. JENS SCHOU
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HVIDBERG, E., SCHOU, J. Subcutaneous Absorption of Urethane in Dehydrated and Fasted Mice. Nature 184, 646–647 (1959). https://doi.org/10.1038/184646a0

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