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Effect of Norleucine and Related Compounds on Growth of the White Rat

Abstract

IT was recently reported from this laboratory that the inclusion of 2 per cent DL-norleucine in the diet greatly inhibited the utilization of D-leucine by rats1. In view of this observation it was of considerable interest to determine whether the antagonistic effect of norleucine on leucine utilization was limited to the D-isomer of the latter.

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References

  1. Rechcigl, jun., M., Loosli, J. K., and Williams, H. H., Science, 127, 1051 (1958).

    Article  ADS  CAS  Google Scholar 

  2. Rechigl, jun., M., Loosli, J. K., and Williams, H. H., J. Biol. Chem., 231, 829 (1958).

    Google Scholar 

  3. Consden, R., Gordon, A. H., Martin, A. J. P., Rosenheim, O., and Synge, R. L. M., Biochem. J., 39, 251 (1945).

    Article  CAS  Google Scholar 

  4. Hassan, M., and Greenberg, D. M., Arch. Biochem. Biophys., 39, 129 (1952).

    Article  Google Scholar 

  5. Butts, J. S., Blunden, H., and Dunn, M. S., J. Biol. Chem., 120, 289 (1937).

    CAS  Google Scholar 

  6. Greenwald, I., J. Biol. Chem., 25, 81 (1916).

    CAS  Google Scholar 

  7. Cohen, P. P., J. Biol. Chem., 119, 333 (1937).

    CAS  Google Scholar 

  8. Kinnory, D. S., Takeda, Y., and Greenberg, D. M., Biochim. Biophys. Acta, 17, 561 (1955).

    Article  CAS  Google Scholar 

  9. Radhakrishnan, A. N., and Meister, A., J. Biol. Chem., 233, 444 (1958).

    CAS  PubMed  Google Scholar 

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RECHCIGL, M., WILLIAMS, H. & LOOSLI, J. Effect of Norleucine and Related Compounds on Growth of the White Rat. Nature 183, 1519–1520 (1959). https://doi.org/10.1038/1831519a0

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