Abstract
HAPTOGLOBINS are globulins present in normal human plasma which are capable of combining and carrying hæmoglobin. First detected by Polonovsky and Jayle1 in 1938, they became the object of detailed studies, mainly by French authors2. Smithies3, in 1955, studying normal human serum by zone electrophoresis in a starch gel supporting medium, showed that it was possible to differentiate three groups easily when a certain amount of hæmoglobin was added to the serum. It was later demonstrated that this polymorphism was based on electrophoretic differences in the haptoglobins4.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Polonovski, M., and Jayle, M. F., Bull. Soc. Chim. Biol., 21, 66 (1939).
Jayle, M. F., and Boussier, G., Expos. Ann. Biochim. Med., 17, 157 (1955).
Smithies, O., Nature, 175, 307 (1955).
Smithies, O., and Walker, N. F., Nature, 178, 694 (1956).
Allison, A. C., Blumberg, B. S., and ap Rees, Nature, 181, 824 (1958).
Smithies, O., Biochem. J., 61, 629 (1955).
Sutton, H. E., Neel, J. V., Binson, G., and Zuelzer, W. W., Nature, 178, 1287 (1956).
Allison, A. G., and ap Rees, W., Brit. Med. J., ii, 1137 (1957).
Bearn, A. G., and Franklin, E. C., Science, 128, 596 (1958).
Smithies, O., and Walker, N. F., Nature, 176, 1265 (1955).
Laurell, A. B., and Grubb, R., Vox Sanguinis, 2, 312 (1957).
Harris, H., Robson, E. B., and Siniscalco, M., Nature, 182, 1324 (1958).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GALLANGO DE RODRÍGUEZ, M., ARENDS, T. Distribution of Haptoglobins in Native Venezuelans. Nature 183, 1465–1466 (1959). https://doi.org/10.1038/1831465a0
Issue Date:
DOI: https://doi.org/10.1038/1831465a0
This article is cited by
-
Haptoglobin and Transferrin Types in Peruvian Indians
Nature (1961)
-
Die Haptoglobintypen Methodik ihrer Bestimmung, Allelenhäufigkeit in einigen Stichproben
Blut Zeitschrift für die Gesamte Blutforschung (1961)
-
Zur Verteilung der Haptoglobintypen in Bayern
Blut Zeitschrift für die Gesamte Blutforschung (1959)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
