Abstract
STUDIES concerning the role of free-radical reactions in biological processes have long been hampered by the lack of a method for detecting free radicals in biological systems. The recent investigations of Commoner1 have shown that electron spin resonance techniques offer considerable promise for this purpose. This communication describes, first, an investigation of sample preparation and handling methods, and second, a qualitative comparison of electron spin resonance signal intensities from normal rat liver tissue with Novikoff rat hepatoma.
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References
Commoner, B., Townsend, J., and Pake, G., Nature, 174, 689 (1954).
Miyagawa, I., Gordy, W., Watabe, N., and Wilbur, K., Proc. U.S. Nat. Acad. Sci., 44, 613 (1958).
Heggen, G., and Strock, L., Anal. Chem., 25, 859 (1953).
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TRUBY, F., GOLDZIEHER, J. Electron Spin Resonance Investigations of Rat Liver and Rat Hepatoma. Nature 182, 1371–1372 (1958). https://doi.org/10.1038/1821371b0
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DOI: https://doi.org/10.1038/1821371b0
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