Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

A Crystalline Material with Xanthine Oxidase Activity

Nature volume 173, pages 1230–1231 (1954)Cite this article

Abstract

IN the course of investigations into the preparation, purification and chemistry of xanthine oxidase from cow's milk, as part of a larger programme of biological and chemical research into functional and structural cellular constituents, we obtained a crystalline material with pronounced enzyme activity.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Ball, E. G., J. Biol. Chem., 128, 51 (1939).

    CAS  Google Scholar 

  2. Horecker, B. L., and Heppel, L. A., J. Biol. Chem., 178, 683 (1949).

    CAS  PubMed  Google Scholar 

  3. Hoch, F. L., and Vallee, B. L., Anal. Chem., 25, 317 (1953).

    Article  CAS  Google Scholar 

  4. Kalckar, H. M., J. Biol. Chem., 167, 429 et seq. (1947).

    CAS  Google Scholar 

  5. Morell, D. B., Biochem. J., 51, 657 (1952).

    Article  CAS  Google Scholar 

  6. Corran, H. S., Dewan, J. G., Gordon, A. H., and Green, D. E., Biochem. J., 33, 1694 (1939).

    Article  CAS  Google Scholar 

  7. See ref. 6; addendum by Philpot, J. St. L.

  8. Green, D. E., and Beinert, H., Biochim. Biophys. Acta, 11, 599 (1953).

    Article  CAS  Google Scholar 

  9. Richert, D. A., and Westerfeld, W. W., J. Biol. Chem., 203, 915 (1953).

    CAS  Google Scholar 

  10. Burch, H. B., Bessy, O. A., and Lowry, O. H., J. Biol. Chem., 175, 457 (1948).

    CAS  PubMed  Google Scholar 

  11. Totter, J. R., Burnett, jun., W. T., Monroe, R. A., Whitney, I. B., and Comar, C. L., Science, 118, 555 (1953).

    Article  ADS  CAS  Google Scholar 

  12. Richert, D. A., Fed. Proc., 13, 279 (1954).

    Google Scholar 

  13. Keilin, D., and Hartree, E. F., Biochem. J., 39, 289 (1945).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Chester Beatty Research Institute, Institute of Cancer Research: Royal Cancer Hospital, Fulham Road, London, S.W.3.

    P. G. AVIS, F. BERGEL, R. C. BRAY & K. V. SHOOTER

Authors
  1. P. G. AVIS
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F. BERGEL
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. C. BRAY
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. V. SHOOTER
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

AVIS, P., BERGEL, F., BRAY, R. et al. A Crystalline Material with Xanthine Oxidase Activity. Nature 173, 1230–1231 (1954). https://doi.org/10.1038/1731230a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1731230a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing