Abstract
IN a recent communication, Polson1 indicated that the small animal viruses fall into definite weight-groups as calculated from their sedimentation constants, using the usual assumptions regarding density and particle shape. The particle weights are multiples of 1, 4, 16 and 64 of a basic unit, 12 mµ in diameter. Soluble antigen which itself is non-infective has been recovered from tissues infected with a variety of virus. It is of particular interest that those soluble antigens which have been measured are all approximately 12 mµ in diameter (influenza2, rabies3 and African horsesickness virus4).
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References
Polson, A., Nature, 172, 1154 (1953).
Hoyle, L., Reed, R., and Astbury, W. T., Nature, 171, 256 (1953).
Polson, A., and Wessels, P. O., Proc. Soc. Exp. Biol. and Med., 84, 317 (1953).
Polson, A., and Madsen, T. (to be published).
Polson, A., and Linder, A. M., Biochim. et Biophys. Acta, 11, 199 (1953).
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NAUDÉ, W., MADSEN, T. & POLSON, A. Different-sized Infective Particles of Rift Valley Fever Virus. Nature 173, 1051–1052 (1954). https://doi.org/10.1038/1731051a0
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DOI: https://doi.org/10.1038/1731051a0
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