Abstract
IN 1949, Ganguly1 observed the presence of an enzyme in pig pancreas capable of hydrolysing vitamin A ester. Recently, McGugan and Laughland2 have demonstrated vitamin A esterase activity in rat-liver homogenates. Observations in this laboratory fully confirm this report, and show that the activity is located in the microsomal fraction of the homogenate.
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References
Ganguly, J., Ph.D. thesis, University of Reading (1949).
McGugan, W. A., and Laughland, D. H., Arch. Biochem. Biophys., 35, 428 (1952).
“United States Pharmacopeia”, 14, 789 (1950).
Potter, V. R., and Elvehjem, C. A., J. Biol. Chem., 114, 495 (1936).
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Ganguly, J., Krinsky, N. I., Mehl, J. W., and Deuel, jun., H. J., Arch. Biochem. Biophys., 38, 275 (1952).
Omachi, A., Barnum, C. P., and Glick, D., Proc. Soc. Exp. Biol., N.Y., 67, 133 (1948).
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GANGULY, J., DEUEL, H. Intracellular Distribution of Vitamin A Esterase Activity in Rat Liver. Nature 172, 120–121 (1953). https://doi.org/10.1038/172120a0
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DOI: https://doi.org/10.1038/172120a0
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