Abstract
DURING investigations in this laboratory on the fate of foreign organic compounds in locusts, we wished to find out whether these insects formed conjugated glucuronic acids. In the higher animals, glucuronic acid conjugation appears to be a major detoxication mechanism particularly for hydroxy compounds1; but there appears to be no record in the literature of this mechanism occurring in invertebrates.
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References
Williams, R. T., “Detoxication Mechanisms” (Chapman and Hall, 1947).
Williams, R. T., Biochem. J., 37, 329 (1943); Smith, J. N. (unpublished data).
Robinson, D., Smith, J. N., and Williams, R. T., Biochem. J., 53, 125 (1953).
Hill, R., Ann. Rep. Chem. Soc., 37, 434 (1940). Pigman, W. W., and Goepp, R. M., “Chemistry of the Carbohydrates”, 509 (Academic Press, Inc., New York, 1948).
Latham, H. G., May, E. L., and Mosettig, E., J. Org. Chem., 15, 884 (1950).
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MYERS, C., SMITH, J. Formation of Glucosides from Phenols in Locusts. Nature 172, 32–33 (1953). https://doi.org/10.1038/172032a0
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DOI: https://doi.org/10.1038/172032a0
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