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Unusual cytomegalovirus complications after autologous stem cell transplantation for large B cell lymphoma: massive gastrointestinal hemorrhage followed by a communicating hydrocephalus

Bone Marrow Transplantation volume 29, pages 715–716 (2002)Cite this article

Abstract

Unusual cytomegalovirus (CMV)-related complications were seen after autologous stem cell transplantation (SCT) in a 50-year-old patient with diffuse large B cell lymphoma. One month after SCT, the patient developed life-threatening upper gastrointestinal tract (GIT) bleeding with several episodes of hemorrhagic shock. Endoscopy and subsequent explorative laparotomy revealed deep-seated bleeding ulcers containing intracellular CMV inclusion bodies distributed extensively in the GIT, from the lower esophagus to the small bowel. Later, she developed gradual loss of consciousness with communicating hydrocephalus which was possibly secondary to CMV-induced ventriculitis. She recovered completely after insertion of a ventriculostomy and subsequent V-P shunt.

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Authors and Affiliations

  1. Department of Hematology Hadassah University Hospital, Jerusalem, Israel

    Y Cohen, N Da'as & A Polliack

  2. Department of Social Medicine, Hadassah University Hospital, Jerusalem, Israel

    O Paltiel

  3. Department of Pathology, Hadassah University Hospital, Jerusalem, Israel

    G Amir

  4. Department of Pediatrics, Hadassah University Hospital, Jerusalem, Israel

    D Engelhard

Authors
  1. Y Cohen
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  2. O Paltiel
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  3. G Amir
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  4. N Da'as
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  5. D Engelhard
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  6. A Polliack
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Cohen, Y., Paltiel, O., Amir, G. et al. Unusual cytomegalovirus complications after autologous stem cell transplantation for large B cell lymphoma: massive gastrointestinal hemorrhage followed by a communicating hydrocephalus. Bone Marrow Transplant 29, 715–716 (2002). https://doi.org/10.1038/sj.bmt.1703519

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  • DOI: https://doi.org/10.1038/sj.bmt.1703519

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