Abstract
Toxoplasma gondii infection reactivation predominantly occurs among patients after allogeneic haematopoietic stem cell transplantation. Mostly, reactivation occurs during first 3 months after transplant, especially when risk factors are present. We report a case of late cerebral toxoplasmosis reactivation, which was probably triggered by a brief course of corticosteroids, administered for chronic graft-versus-host disease (cGVHD). In the presence of risk factors, such as cGVHD, prophylactic treatment for toxoplasmosis should be reinstituted; Trimethoprim-sulfamethoxasole most probably prevented earlier reactivation of toxoplasmosis in our patient.
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Zver, S., Černelč, P., Mlakar, U. et al. Cerebral toxoplasmosis – a late complication of allogeneic haematopoietic stem cell transplantation. Bone Marrow Transplant 24, 1363–1365 (1999). https://doi.org/10.1038/sj.bmt.1702075
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DOI: https://doi.org/10.1038/sj.bmt.1702075
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