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Successful prevention of hematological relapse for a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic bone marrow transplantation by donor leukocyte infusion

Bone Marrow Transplantation volume 19, pages 393–394 (1997)Cite this article

Abstract

Donor leukocyte infusion (DLI) was carried out on a 12-year-old girl with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who received allogeneic bone marrow transplantation from an HLA-identical sibling. This is the first report of DLI use before the onset of hematological relapse monitored by the results of RT-PCR. This patient has been in CR for 11 months after BMT, suggesting this alternative treatment is promising for Ph+ ALL with positive reverse transcriptase-polymerase chain reaction (RT-PCR) following BMT.

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  1. Department of Pediatrics, Nagoya City University Medical School, Nagoya, Japan

    M Yazaki, M Andoh, T Ito, T Ohno & Y Wada

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  1. M Yazaki
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  2. M Andoh
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  3. T Ito
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  4. T Ohno
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  5. Y Wada
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Yazaki, M., Andoh, M., Ito, T. et al. Successful prevention of hematological relapse for a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic bone marrow transplantation by donor leukocyte infusion. Bone Marrow Transplant 19, 393–394 (1997). https://doi.org/10.1038/sj.bmt.1700663

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  • DOI: https://doi.org/10.1038/sj.bmt.1700663

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