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Coenzyme A as a Co-factor of the Pyruvate Dehydrogenase System of Cl. saccharobutyricum

Nature volume 169, pages 709–711 (1952)Cite this article

Abstract

It has previously been shown that cell-free extracts of Cl. saccharobutyricum GR4 and Cl. sporogenes GO1 (prepared by disruption in an ultrasonic oscillator) have high pyruvate dehydrogenase activity under both aerobic and anaerobic conditions1, in the former case oxygen being the hydrogen acceptor. Methylene blue is decolorized during the reaction, even under aerobic conditions.

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References

  1. Nisman, B., C.R. Acad. Sci., Paris, 230, 248 (1950).

    Google Scholar 

  2. Nisman, B. (unpublished results).

  3. Lipmann, F., and Tuttle, L. C., J. Biol. Chem., 159, 21 (1945).

    CAS  Google Scholar 

  4. Chou, T. C., Novelli, G. D., Stadtman, E. R., and Lipmann, F., Fed. Proc., 9, 160 (1950).

    Google Scholar 

  5. Stadtman, E. R., Fed. Proc., 9, 233 (1950).

    Google Scholar 

  6. Lipmann, F., Cold Spring Harbor Symp. Quant. Biol., 7, 248 (1939).

    Article  CAS  Google Scholar 

  7. Chantrenne, H., and Lipmann, F., J. Biol. Chem., 187, 757 (1950).

    CAS  PubMed  Google Scholar 

  8. Ochoa, S., Physiol. Rev., 31, 56 (1951).

    Article  CAS  PubMed  Google Scholar 

  9. Korkes, S., Stern, J. R., Gunsalus, I. C., and Ochoa, S., Nature, 166, 439 (1950).

    Article  ADS  CAS  PubMed  Google Scholar 

  10. Cohen, G. N., and Cohen-Bazire, G., Nature, 166, 1077 (1950).

    Article  ADS  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Laboratoire de chimie bactérienne, Service des anaérobies, Institut Pasteur, Garches (Seine et Oise),

    B. NISMAN & J. MAGER

Authors
  1. B. NISMAN
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  2. J. MAGER
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NISMAN, B., MAGER, J. Coenzyme A as a Co-factor of the Pyruvate Dehydrogenase System of Cl. saccharobutyricum. Nature 169, 709–711 (1952). https://doi.org/10.1038/169709a0

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  • DOI: https://doi.org/10.1038/169709a0

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