Abstract
WHEN a peripheral nerve is cut, the portion of the nerve distal to the point of section undergoes a series of changes characteristic of Wallerian degeneration. The axon and, later, the myelin sheath are destroyed and there is an increase in the number of both Schwann cells and endoneurial cells (chiefly fibrocytes and macrophages) found along the course of the nerve1,2. We have now shown that in such a degenerating peripheral nerve there is a marked increase in the activity of the enzyme β-glucuronidase.
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HOLLINGER, D., LOGAN, J., MANNELL, W. et al. β-Glucuronidase Activity of Peripheral Nerve during Wallerian Degeneration. Nature 169, 670 (1952). https://doi.org/10.1038/169670a0
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DOI: https://doi.org/10.1038/169670a0
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