Abstract
IN a recent communication, Grigg1 has discussed the possibility of an interconidial inhibition in Neurospora, conidia of biochemically deficient mutant strains inhibiting the growth of wild-type conidia. It was demonstrated that large numbers of mutant conidia inhibit the growth of wild-type conidia by mixing varying concentrations of mutant conidia with small aliquots of wild-type conidia and subsequent plating on ‘minimal’ medium. The mutant conidia will not grow on minimal medium, although they germinate; the wild-type conidia should grow normally. Using, for example, an adenineless mutant (W40) of a macroconidial strain, 100 per cent inhibition of wild-type conidia was observed in the presence of 4 × 107 adenineless conidia per plate, whereas no inhibition was found in the presence of 2 × 107 adenineless conidia.
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Grigg, G. W., Nature, 169, 98 (1952).
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KøLMARK, G., WESTERGAARD, M. Validity of the Neurospora Back-Mutation Test. Nature 169, 626 (1952). https://doi.org/10.1038/169626a0
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DOI: https://doi.org/10.1038/169626a0
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