Abstract
THE demonstration of the property of hot trichloracetic acid in bringing about the dissociation of nucleic acid from nucleoproteins by Schneider1 has led many authors in recent years to use it in different cytochemical experiments2–4. The protein framework of the chromosomes thus liberated provides a useful substrate for several biochemical procedures. Both ribo- and deoxyribo-nucleoproteins have been found to be affected by such treatments.
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References
Schneider, W. C., J. Biol. Chem., 161, 293 (1945).
Pollister, A. W., and Ris, H., Symp. Quant. Biol. Cold Spr. Harb., 12, 147 (1947).
Sharma, A. K., Nature, 167, 441 (1951).
Kaufmann, B. P., Gay, H., and McDonald, M. R., Amer. J. Bot., 38, 268 (1951).
Bhaduri, P. N., J. Roy. Micro. Soc., 58, 120 (1938).
Brachet, J., C.R. Soc. Biol., Paris, 133, 88 (1940).
Kurnick, N. B., J. Gen. Physiol., 33, 243 (1950).
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SHARMA, A., BHATTACHARJEE, D. Effect of Trichloracetic Acid on Nuclear Proteins. Nature 169, 417–418 (1952). https://doi.org/10.1038/169417b0
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DOI: https://doi.org/10.1038/169417b0
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